HCSGD entry for TMC1
1. General information
| Official gene symbol | TMC1 |
|---|---|
| Entrez ID | 117531 |
| Gene full name | transmembrane channel-like 1 |
| Other gene symbols | DFNA36 DFNB11 DFNB7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006811 | Ion transport | IEA | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032426 | Stereocilium bundle tip | IEA | cellular_component |
| GO:0050910 | Detection of mechanical stimulus involved in sensory perception of sound | IEA | biological_process |
| GO:0060005 | Vestibular reflex | IEA | biological_process |
| GO:0060117 | Auditory receptor cell development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4726619353 | 0.9069249117 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0109215219 |
| GSE13712_SHEAR | Up | 0.2523576443 |
| GSE13712_STATIC | Up | 0.0219751528 |
| GSE19018 | Up | 0.0309081151 |
| GSE19899_A1 | Up | 0.1610737470 |
| GSE19899_A2 | Down | -0.1545745116 |
| PubMed_21979375_A1 | Up | 0.2505976556 |
| PubMed_21979375_A2 | Up | 0.1316796539 |
| GSE35957 | Up | 0.3854124419 |
| GSE36640 | Up | 0.1330015508 |
| GSE54402 | Up | 0.0221161387 |
| GSE9593 | Down | -0.1192152722 |
| GSE43922 | Up | 0.1261187775 |
| GSE24585 | Up | 0.1629293613 |
| GSE37065 | Up | 0.0459221163 |
| GSE28863_A1 | Down | -0.0518781744 |
| GSE28863_A2 | Down | -0.1147326896 |
| GSE28863_A3 | Up | 0.0272981705 |
| GSE28863_A4 | Down | -0.0075563461 |
| GSE48662 | Down | -0.0388533654 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
