HCSGD entry for IP6K3
1. General information
| Official gene symbol | IP6K3 |
|---|---|
| Entrez ID | 117283 |
| Gene full name | inositol hexakisphosphate kinase 3 |
| Other gene symbols | IHPK3 INSP6K3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000831 | Inositol hexakisphosphate 6-kinase activity | IDA | molecular_function |
| GO:0000832 | Inositol hexakisphosphate 5-kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0008440 | Inositol-1,4,5-trisphosphate 3-kinase activity | IEA | molecular_function |
| GO:0032958 | Inositol phosphate biosynthetic process | IDA | biological_process |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046488 | Phosphatidylinositol metabolic process | IDA | biological_process |
| GO:0052723 | Inositol hexakisphosphate 1-kinase activity | IEA | molecular_function |
| GO:0052724 | Inositol hexakisphosphate 3-kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7178543634 | 0.5545475210 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0128658900 |
| GSE13712_SHEAR | Up | 0.0480847873 |
| GSE13712_STATIC | Down | -0.1651873567 |
| GSE19018 | Down | -0.3809719912 |
| GSE19899_A1 | Up | 0.0015576172 |
| GSE19899_A2 | Up | 0.2912251790 |
| PubMed_21979375_A1 | Down | -0.4670660929 |
| PubMed_21979375_A2 | Up | 0.1667078832 |
| GSE35957 | Up | 0.1238330010 |
| GSE36640 | Up | 0.2259047027 |
| GSE54402 | Down | -0.1766507825 |
| GSE9593 | Down | -0.0373813726 |
| GSE43922 | Up | 0.0226829265 |
| GSE24585 | Down | -0.0375001219 |
| GSE37065 | Down | -0.0106311583 |
| GSE28863_A1 | Down | -0.1390430038 |
| GSE28863_A2 | Up | 0.0567462457 |
| GSE28863_A3 | Up | 0.1276233001 |
| GSE28863_A4 | Up | 0.2027409918 |
| GSE48662 | Down | -0.0267545420 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-330-5p | MIMAT0004693 | MIRT038242 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
