HCSGD entry for THEM4
1. General information
| Official gene symbol | THEM4 |
|---|---|
| Entrez ID | 117145 |
| Gene full name | thioesterase superfamily member 4 |
| Other gene symbols | CTMP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006631 | Fatty acid metabolic process | IDA | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0016290 | Palmitoyl-CoA hydrolase activity | IDA | molecular_function |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043491 | Protein kinase B signaling | IMP | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
| GO:1902108 | Regulation of mitochondrial membrane permeability involved in apoptotic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4624557920 | 0.3015535846 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0635580998 |
| GSE13712_SHEAR | Up | 0.6188332928 |
| GSE13712_STATIC | Up | 0.4323703104 |
| GSE19018 | Down | -0.1334977632 |
| GSE19899_A1 | Down | -0.1284888306 |
| GSE19899_A2 | Up | 0.7043602144 |
| PubMed_21979375_A1 | Up | 0.5992657973 |
| PubMed_21979375_A2 | Up | 0.1375432427 |
| GSE35957 | Up | 0.2389260949 |
| GSE36640 | Down | -0.2860388648 |
| GSE54402 | Down | -0.2495944900 |
| GSE9593 | Down | -0.1202724674 |
| GSE43922 | Up | 0.0456216504 |
| GSE24585 | Down | -0.1811218001 |
| GSE37065 | Down | -0.0040018020 |
| GSE28863_A1 | Down | -0.1560618850 |
| GSE28863_A2 | Up | 0.1867971237 |
| GSE28863_A3 | Down | -0.3971424101 |
| GSE28863_A4 | Down | -0.3337503679 |
| GSE48662 | Down | -0.0926754688 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005171 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031745 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
