HCSGD entry for APOA5

1. General information

Official gene symbolAPOA5
Entrez ID116519
Gene full nameapolipoprotein A-V
Other gene symbolsAPOAV RAP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005543Phospholipid bindingIDAmolecular_function
GO:0005576Extracellular regionIDA TAScellular_component
GO:0005615Extracellular spaceIDA IEAcellular_component
GO:0006641Triglyceride metabolic processIDA IEA IMPbiological_process
GO:0006869Lipid transportIDA IEAbiological_process
GO:0008047Enzyme activator activityIDAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0008289Lipid bindingIDA IEAmolecular_function
GO:0009725Response to hormoneIEAbiological_process
GO:0010898Positive regulation of triglyceride catabolic processIDAbiological_process
GO:0010902Positive regulation of very-low-density lipoprotein particle remodelingIDAbiological_process
GO:0019433Triglyceride catabolic processIMPbiological_process
GO:0019899Enzyme bindingIDAmolecular_function
GO:0031100Organ regenerationIEAbiological_process
GO:0031210Phosphatidylcholine bindingIDAmolecular_function
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034362Low-density lipoprotein particleIDAcellular_component
GO:0034364High-density lipoprotein particleIDAcellular_component
GO:0034370Triglyceride-rich lipoprotein particle remodelingIEAbiological_process
GO:0035473Lipase bindingIPImolecular_function
GO:0042157Lipoprotein metabolic processIEAbiological_process
GO:0042246Tissue regenerationIEPbiological_process
GO:0042627ChylomicronIDAcellular_component
GO:0042632Cholesterol homeostasisIDAbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045723Positive regulation of fatty acid biosynthetic processIDAbiological_process
GO:0048260Positive regulation of receptor-mediated endocytosisTASbiological_process
GO:0050750Low-density lipoprotein particle receptor bindingIPImolecular_function
GO:0050996Positive regulation of lipid catabolic processIDAbiological_process
GO:0051006Positive regulation of lipoprotein lipase activityIDAbiological_process
GO:0055090Acylglycerol homeostasisIDA IEA IMPbiological_process
GO:0060229Lipase activator activityIMPmolecular_function
GO:0060230Lipoprotein lipase activator activityIDAmolecular_function
GO:0070325Lipoprotein particle receptor bindingIPImolecular_function
GO:0070328Triglyceride homeostasisIDA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38760297480.94105315150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0444625629
GSE13712_SHEARDown-0.0447278811
GSE13712_STATICDown-0.0596257245
GSE19018Up0.0112916729
GSE19899_A1Up0.1391097257
GSE19899_A2Up0.1263491198
PubMed_21979375_A1Up0.1881172582
PubMed_21979375_A2Down-0.0454130168
GSE35957Up0.2248516295
GSE36640Up0.1091138099
GSE54402Up0.0447708394
GSE9593Up0.0022393889
GSE43922Up0.0248144158
GSE24585Up0.0177307745
GSE37065Down-0.0027248951
GSE28863_A1Up0.1635674069
GSE28863_A2Up0.0426059732
GSE28863_A3Up0.3560233003
GSE28863_A4Up0.1144126139
GSE48662Up0.0211506027

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.