HCSGD entry for TSEN15
1. General information
| Official gene symbol | TSEN15 |
|---|---|
| Entrez ID | 116461 |
| Gene full name | tRNA splicing endonuclease 15 homolog (S. cerevisiae) |
| Other gene symbols | C1orf19 sen15 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000213 | TRNA-intron endonuclease activity | IEA | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006388 | TRNA splicing, via endonucleolytic cleavage and ligation | IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9984356597 | 0.0004948482 | 0.9999902473 | 0.0411066038 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5618261065 |
| GSE13712_SHEAR | Down | -0.6062860761 |
| GSE13712_STATIC | Down | -0.2626724554 |
| GSE19018 | Up | 0.2575770792 |
| GSE19899_A1 | Down | -1.3797991946 |
| GSE19899_A2 | Down | -2.1083266187 |
| PubMed_21979375_A1 | Down | -1.9945589631 |
| PubMed_21979375_A2 | Down | -3.5763242773 |
| GSE35957 | Down | -0.4227241575 |
| GSE36640 | Down | -1.2722865731 |
| GSE54402 | Down | -0.6330536723 |
| GSE9593 | Down | -0.0921616093 |
| GSE43922 | Down | -1.3281196739 |
| GSE24585 | Down | -0.1074872011 |
| GSE37065 | Down | -0.4205608617 |
| GSE28863_A1 | Down | -0.2424535952 |
| GSE28863_A2 | Down | -0.1159883124 |
| GSE28863_A3 | Down | -0.2188440757 |
| GSE28863_A4 | Down | -0.0654840759 |
| GSE48662 | Down | -0.3648375378 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT044997 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052033 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
