HCSGD entry for GRIN3B

1. General information

Official gene symbolGRIN3B
Entrez ID116444
Gene full nameglutamate receptor, ionotropic, N-methyl-D-aspartate 3B
Other gene symbolsGluN3B NR3B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004970Ionotropic glutamate receptor activityIEAmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005261Cation channel activityISSmolecular_function
GO:0005262Calcium channel activityISSmolecular_function
GO:0007268Synaptic transmissionISSbiological_process
GO:0016594Glycine bindingISSmolecular_function
GO:0017146N-methyl-D-aspartate selective glutamate receptor complexISS NAScellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030594Neurotransmitter receptor activityISSmolecular_function
GO:0035235Ionotropic glutamate receptor signaling pathwayISSbiological_process
GO:0042165Neurotransmitter bindingISSmolecular_function
GO:0043025Neuronal cell bodyISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051205Protein insertion into membraneISSbiological_process
GO:0051924Regulation of calcium ion transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53553548120.66407001250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1592006347
GSE13712_SHEARDown-0.1272462188
GSE13712_STATICDown-0.0817165309
GSE19018Up0.0962145933
GSE19899_A1Down-0.1740827964
GSE19899_A2Up0.0707093850
PubMed_21979375_A1Up0.1523493354
PubMed_21979375_A2Down-0.2268310881
GSE35957Up0.2255985262
GSE36640Up0.0396817225
GSE54402Down-0.0762968679
GSE9593Down-0.1050624991
GSE43922Up0.0501618296
GSE24585Up0.2177878564
GSE37065Down-0.0113491691
GSE28863_A1Down-0.0895094006
GSE28863_A2Down-0.0804130150
GSE28863_A3Up0.4899808126
GSE28863_A4Up0.0936426404
GSE48662Up0.3052836786

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
GlycineDB00145 NUTR00028
TenocyclidineDB01520 -
AcamprosateDB00659 APRD00661
GavestinelDB06741 -
AtomoxetineDB00289 APRD00614
PentobarbitalDB00312 APRD01174
GabapentinDB00996 APRD00015
DehydroepiandrosteroneDB01708 EXPT00519 | DB06593
MilnacipranDB04896 -
KetobemidoneDB06738 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.