HCSGD entry for CTHRC1
1. General information
| Official gene symbol | CTHRC1 |
|---|---|
| Entrez ID | 115908 |
| Gene full name | collagen triple helix repeat containing 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005109 | Frizzled binding | IEA | molecular_function |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0016477 | Cell migration | IEA | biological_process |
| GO:0017147 | Wnt-protein binding | IEA | molecular_function |
| GO:0031012 | Extracellular matrix | IEA | cellular_component |
| GO:0032092 | Positive regulation of protein binding | IEA | biological_process |
| GO:0033690 | Positive regulation of osteoblast proliferation | IEA | biological_process |
| GO:0043932 | Ossification involved in bone remodeling | IEA | biological_process |
| GO:0045669 | Positive regulation of osteoblast differentiation | IEA | biological_process |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | IEA | biological_process |
| GO:0060122 | Inner ear receptor stereocilium organization | IEA | biological_process |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IEA | biological_process |
| GO:0090103 | Cochlea morphogenesis | IEA | biological_process |
| GO:0090177 | Establishment of planar polarity involved in neural tube closure | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8555583412 | 0.0008566468 | 0.9999902473 | 0.0558200495 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4946763097 |
| GSE13712_SHEAR | Down | -0.7755180403 |
| GSE13712_STATIC | Down | -0.3645851541 |
| GSE19018 | Down | -4.9575030250 |
| GSE19899_A1 | Down | -1.2976616853 |
| GSE19899_A2 | Down | -1.2394834933 |
| PubMed_21979375_A1 | Down | -2.0306628492 |
| PubMed_21979375_A2 | Down | -1.2456401233 |
| GSE35957 | Up | 0.1716568908 |
| GSE36640 | Down | -0.0711488684 |
| GSE54402 | Down | -0.1510458759 |
| GSE9593 | Up | 1.0787789749 |
| GSE43922 | Up | 0.0092428033 |
| GSE24585 | Up | 0.2683064321 |
| GSE37065 | Up | 0.1851160497 |
| GSE28863_A1 | Down | -0.3388311064 |
| GSE28863_A2 | Down | -0.5695212742 |
| GSE28863_A3 | Down | -0.4200924356 |
| GSE28863_A4 | Down | -0.2278947713 |
| GSE48662 | Down | -0.6113429122 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018001 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019329 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022682 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
