HCSGD entry for CIRBP
1. General information
| Official gene symbol | CIRBP |
|---|---|
| Entrez ID | 1153 |
| Gene full name | cold inducible RNA binding protein |
| Other gene symbols | CIRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0009409 | Response to cold | IEA | biological_process |
| GO:0009411 | Response to UV | IDA | biological_process |
| GO:0010494 | Cytoplasmic stress granule | IEA ISS | cellular_component |
| GO:0030371 | Translation repressor activity | IEA ISS | molecular_function |
| GO:0034063 | Stress granule assembly | IEA ISS | biological_process |
| GO:0045727 | Positive regulation of translation | IDA | biological_process |
| GO:0048255 | MRNA stabilization | IDA | biological_process |
| GO:0070181 | SSU rRNA binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7232993199 | 0.0158668174 | 0.9999902473 | 0.2461176678 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0221337268 |
| GSE13712_SHEAR | Down | -0.3746482906 |
| GSE13712_STATIC | Down | -0.1485968581 |
| GSE19018 | Down | -0.0467275188 |
| GSE19899_A1 | Down | -0.5538218956 |
| GSE19899_A2 | Down | -0.7007852525 |
| PubMed_21979375_A1 | Down | -1.5518224113 |
| PubMed_21979375_A2 | Down | -0.7554306999 |
| GSE35957 | Down | -0.6288506483 |
| GSE36640 | Up | 0.1941428653 |
| GSE54402 | Down | -0.6003782478 |
| GSE9593 | Down | -0.1677579025 |
| GSE43922 | Down | -0.8319239379 |
| GSE24585 | Up | 0.9948212445 |
| GSE37065 | Down | -0.4263274972 |
| GSE28863_A1 | Up | 0.3805732326 |
| GSE28863_A2 | Up | 0.0685263795 |
| GSE28863_A3 | Up | 0.2043276604 |
| GSE28863_A4 | Up | 0.1347339426 |
| GSE48662 | Down | -0.0363643152 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028434 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030423 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
