HCSGD entry for ATG4A
1. General information
| Official gene symbol | ATG4A |
|---|---|
| Entrez ID | 115201 |
| Gene full name | autophagy related 4A, cysteine peptidase |
| Other gene symbols | APG4A AUTL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IDA IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0012893165 | 0.9343463660 | 0.0972381089 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.5003469120 |
| GSE13712_SHEAR | Up | 0.3342240519 |
| GSE13712_STATIC | Up | 0.6624165656 |
| GSE19018 | Up | 0.1567017041 |
| GSE19899_A1 | Up | 0.6857892361 |
| GSE19899_A2 | Up | 1.1743342078 |
| PubMed_21979375_A1 | Up | 1.0847281169 |
| PubMed_21979375_A2 | Up | 1.1523488578 |
| GSE35957 | Up | 0.5351949023 |
| GSE36640 | Up | 1.5211519797 |
| GSE54402 | Up | 0.3938313602 |
| GSE9593 | Up | 0.2165579090 |
| GSE43922 | Up | 0.5924850574 |
| GSE24585 | Up | 0.4607473629 |
| GSE37065 | Up | 0.1030853817 |
| GSE28863_A1 | Down | -0.4802690738 |
| GSE28863_A2 | Down | -0.0938027146 |
| GSE28863_A3 | Down | -0.9031480449 |
| GSE28863_A4 | Up | 0.2788515712 |
| GSE48662 | Down | -0.1783122025 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022814 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024785 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026607 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036957 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
