HCSGD entry for ADCY9
1. General information
| Official gene symbol | ADCY9 |
|---|---|
| Entrez ID | 115 |
| Gene full name | adenylate cyclase 9 |
| Other gene symbols | AC9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004016 | Adenylate cyclase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006833 | Water transport | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007189 | Adenylate cyclase-activating G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007202 | Activation of phospholipase C activity | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0009190 | Cyclic nucleotide biosynthetic process | IEA | biological_process |
| GO:0016849 | Phosphorus-oxygen lyase activity | IEA | molecular_function |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0034199 | Activation of protein kinase A activity | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1968658524 | 0.2555322138 | 0.8583246811 | 0.9694239550 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0749947875 |
| GSE13712_SHEAR | Up | 0.3572364855 |
| GSE13712_STATIC | Up | 0.0458400575 |
| GSE19018 | Up | 0.1391599628 |
| GSE19899_A1 | Down | -0.7495211605 |
| GSE19899_A2 | Up | 0.0278008003 |
| PubMed_21979375_A1 | Down | -0.3136585946 |
| PubMed_21979375_A2 | Up | 0.0769681619 |
| GSE35957 | Up | 0.2925616373 |
| GSE36640 | Up | 0.5228814529 |
| GSE54402 | Down | -0.4100797485 |
| GSE9593 | Up | 0.2971523280 |
| GSE43922 | Down | -0.4905342818 |
| GSE24585 | Down | -0.1773749561 |
| GSE37065 | Down | -0.3405875448 |
| GSE28863_A1 | Up | 0.9715341547 |
| GSE28863_A2 | Up | 0.7049033169 |
| GSE28863_A3 | Down | -0.0577902741 |
| GSE28863_A4 | Down | -0.1451619565 |
| GSE48662 | Up | 0.1325626557 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016333 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022222 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025695 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027498 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032153 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037005 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037595 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-33b-5p | MIMAT0003301 | MIRT039580 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043559 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047729 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048684 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
