HCSGD entry for MYSM1
1. General information
| Official gene symbol | MYSM1 |
|---|---|
| Entrez ID | 114803 |
| Gene full name | Myb-like, SWIRM and MPN domains 1 |
| Other gene symbols | 2A-DUB 2ADUB RP4-592A1.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006338 | Chromatin remodeling | IMP | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | IMP | molecular_function |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0035522 | Monoubiquitinated histone H2A deubiquitination | IMP | biological_process |
| GO:0042393 | Histone binding | IDA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7386601459 | 0.1747768778 | 0.9999902473 | 0.8091689995 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0395456690 |
| GSE13712_SHEAR | Down | -0.4548149510 |
| GSE13712_STATIC | Down | -0.4627738122 |
| GSE19018 | Down | -0.0276051522 |
| GSE19899_A1 | Up | 0.1726449056 |
| GSE19899_A2 | Up | 0.0221297709 |
| PubMed_21979375_A1 | Down | -0.0640879191 |
| PubMed_21979375_A2 | Up | 0.0941843736 |
| GSE35957 | Down | -0.1908617226 |
| GSE36640 | Down | -0.2842477770 |
| GSE54402 | Up | 0.2007292645 |
| GSE9593 | Down | -0.0838177327 |
| GSE43922 | Up | 0.2783792093 |
| GSE24585 | Up | 0.1485078575 |
| GSE37065 | Up | 0.1720364706 |
| GSE28863_A1 | Down | -0.1936000973 |
| GSE28863_A2 | Up | 0.3708152647 |
| GSE28863_A3 | Down | -0.8745974427 |
| GSE28863_A4 | Down | -0.3016915659 |
| GSE48662 | Down | -0.0529995149 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041950 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045259 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
