HCSGD entry for PGLYRP2

1. General information

Official gene symbolPGLYRP2
Entrez ID114770
Gene full namepeptidoglycan recognition protein 2
Other gene symbolsHMFT0141 PGLYRPL PGRP-L PGRPL TAGL-like tagL tagL-alpha tagl-beta
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001519Peptide amidationNASbiological_process
GO:0002221Pattern recognition receptor signaling pathwayIDAbiological_process
GO:0005576Extracellular regionIEAcellular_component
GO:0005622IntracellularNAScellular_component
GO:0007165Signal transductionIDAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008745N-acetylmuramoyl-L-alanine amidase activityIEA TASmolecular_function
GO:0009253Peptidoglycan catabolic processIEAbiological_process
GO:0016019Peptidoglycan receptor activityIDAmolecular_function
GO:0016020MembraneNAScellular_component
GO:0016045Detection of bacteriumIDAbiological_process
GO:0032689Negative regulation of interferon-gamma productionIEAbiological_process
GO:0032827Negative regulation of natural killer cell differentiation involved in immune responseIEAbiological_process
GO:0042834Peptidoglycan bindingIDAmolecular_function
GO:0044117Growth of symbiont in hostIEAbiological_process
GO:0045087Innate immune responseNASbiological_process
GO:0050830Defense response to Gram-positive bacteriumIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46638557430.89956692370.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0401317496
GSE13712_SHEARDown-0.0362174788
GSE13712_STATICDown-0.0431814048
GSE19018Up0.1014745155
GSE19899_A1Up0.0775435338
GSE19899_A2Up0.3060796139
PubMed_21979375_A1Up0.3567312822
PubMed_21979375_A2Down-0.0964624950
GSE35957Up0.1053441185
GSE36640Up0.0004083673
GSE54402Down-0.0471322923
GSE9593Up0.0904539860
GSE43922Up0.0531275994
GSE24585Down-0.0621718677
GSE37065Down-0.0858901702
GSE28863_A1Up0.0842617682
GSE28863_A2Up0.0800681169
GSE28863_A3Up0.2728414605
GSE28863_A4Up0.1341108561
GSE48662Down-0.0347106126

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.