HCSGD entry for CHRNB4

1. General information

Official gene symbolCHRNB4
Entrez ID1143
Gene full namecholinergic receptor, nicotinic, beta 4 (neuronal)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001508Action potentialIEAbiological_process
GO:0004889Acetylcholine-activated cation-selective channel activityIEA TASmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneICcellular_component
GO:0005892Acetylcholine-gated channel complexIDA TAScellular_component
GO:0006811Ion transportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0006939Smooth muscle contractionIEAbiological_process
GO:0006940Regulation of smooth muscle contractionIEAbiological_process
GO:0007165Signal transductionIDAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007271Synaptic transmission, cholinergicTASbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0015276Ligand-gated ion channel activityTASmolecular_function
GO:0015464Acetylcholine receptor activityIDAmolecular_function
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035095Behavioral response to nicotineIEAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0046928Regulation of neurotransmitter secretionNASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060084Synaptic transmission involved in micturitionIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31824503250.93558964330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1814185731
GSE13712_SHEARUp0.1939262479
GSE13712_STATICUp0.0399309517
GSE19018Up0.1098974515
GSE19899_A1Up0.1351666601
GSE19899_A2Up0.3463229982
PubMed_21979375_A1Down-0.4453246665
PubMed_21979375_A2Up0.3034391637
GSE35957Up0.1056717587
GSE36640Up0.1014020311
GSE54402Down-0.1688924528
GSE9593Up0.0748089564
GSE43922Up0.0256974901
GSE24585Up0.1654501471
GSE37065Down-0.2389327626
GSE28863_A1Up0.0692684444
GSE28863_A2Up0.0671015339
GSE28863_A3Up0.1583237942
GSE28863_A4Up0.1279171850
GSE48662Down-0.0283726257

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NicotineDB00184 APRD00200 | EXPT02315 | DB09463
DextromethorphanDB00514 APRD00655
GalantamineDB00674 APRD00206 | EXPT01628
PentoliniumDB01090 APRD00038

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018694MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.