HCSGD entry for GABARAPL2
1. General information
| Official gene symbol | GABARAPL2 |
|---|---|
| Entrez ID | 11345 |
| Gene full name | GABA(A) receptor-associated protein-like 2 |
| Other gene symbols | ATG8 ATG8C GATE-16 GATE16 GEF-2 GEF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IDA IEA ISS | cellular_component |
| GO:0000149 | SNARE binding | ISS | molecular_function |
| GO:0000421 | Autophagic vacuole membrane | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005776 | Autophagic vacuole | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0005829 | Cytosol | ISS | cellular_component |
| GO:0006891 | Intra-Golgi vesicle-mediated transport | ISS | biological_process |
| GO:0006914 | Autophagy | IEA NAS | biological_process |
| GO:0008017 | Microtubule binding | NAS | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0032781 | Positive regulation of ATPase activity | ISS | biological_process |
| GO:0048487 | Beta-tubulin binding | ISS | molecular_function |
| GO:0050811 | GABA receptor binding | ISS NAS | molecular_function |
| GO:0051117 | ATPase binding | ISS | molecular_function |
| GO:1901799 | Negative regulation of proteasomal protein catabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0168499487 | 0.9930389347 | 0.3206851048 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3584332754 |
| GSE13712_SHEAR | Down | -0.1765472920 |
| GSE13712_STATIC | Down | -0.1046473161 |
| GSE19018 | Up | 0.7160709321 |
| GSE19899_A1 | Up | 0.4033436420 |
| GSE19899_A2 | Up | 0.4675805496 |
| PubMed_21979375_A1 | Up | 0.0548603104 |
| PubMed_21979375_A2 | Up | 0.3918389510 |
| GSE35957 | Up | 0.1098937993 |
| GSE36640 | Up | 0.8403009914 |
| GSE54402 | Up | 0.1068219426 |
| GSE9593 | Up | 0.1735814131 |
| GSE43922 | Up | 0.1266782755 |
| GSE24585 | Up | 0.2125793354 |
| GSE37065 | Up | 0.0148999008 |
| GSE28863_A1 | Up | 0.1840229129 |
| GSE28863_A2 | Up | 0.3241101849 |
| GSE28863_A3 | Up | 0.0838672579 |
| GSE28863_A4 | Up | 0.0171904822 |
| GSE48662 | Up | 0.5909912513 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028644 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049629 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
