HCSGD entry for EXOC3
1. General information
| Official gene symbol | EXOC3 |
|---|---|
| Entrez ID | 11336 |
| Gene full name | exocyst complex component 3 |
| Other gene symbols | SEC6 SEC6L1 Sec6p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000145 | Exocyst | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030667 | Secretory granule membrane | TAS | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1464912047 | 0.8084322328 | 0.7667120700 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0953139596 |
| GSE13712_SHEAR | Down | -0.1724515236 |
| GSE13712_STATIC | Down | -0.1719971405 |
| GSE19018 | Up | 0.1133612630 |
| GSE19899_A1 | Down | -0.2991442114 |
| GSE19899_A2 | Down | -0.4008069563 |
| PubMed_21979375_A1 | Up | 0.4457866149 |
| PubMed_21979375_A2 | Up | 0.5277794556 |
| GSE35957 | Up | 0.2032381227 |
| GSE36640 | Down | -0.0704555378 |
| GSE54402 | Up | 0.0351132190 |
| GSE9593 | Down | -0.0259269071 |
| GSE43922 | Down | -0.0672566879 |
| GSE24585 | Up | 0.3712957933 |
| GSE37065 | Down | -0.0002217106 |
| GSE28863_A1 | Up | 0.4331930923 |
| GSE28863_A2 | Up | 0.4281768735 |
| GSE28863_A3 | Up | 0.1762820552 |
| GSE28863_A4 | Down | -0.1085134335 |
| GSE48662 | Up | 0.4758604084 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020798 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023900 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025819 | Microarray | Functional MTI (Weak) | 19073608 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
