HCSGD entry for COPE
1. General information
| Official gene symbol | COPE |
|---|---|
| Entrez ID | 11316 |
| Gene full name | coatomer protein complex, subunit epsilon |
| Other gene symbols | epsilon-COP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | IEA TAS | biological_process |
| GO:0006891 | Intra-Golgi vesicle-mediated transport | ISS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030126 | COPI vesicle coat | ISS | cellular_component |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4489170092 | 0.8577154515 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1441261784 |
| GSE13712_SHEAR | Down | -0.1456871821 |
| GSE13712_STATIC | Up | 0.0684964170 |
| GSE19018 | Down | -0.0247798285 |
| GSE19899_A1 | Up | 0.0205834702 |
| GSE19899_A2 | Up | 0.4124143812 |
| PubMed_21979375_A1 | Up | 0.4336066227 |
| PubMed_21979375_A2 | Up | 0.2838803494 |
| GSE35957 | Down | -0.1350505076 |
| GSE36640 | Up | 0.1184386431 |
| GSE54402 | Up | 0.1521678647 |
| GSE9593 | Up | 0.1258360218 |
| GSE43922 | Up | 0.0570793710 |
| GSE24585 | Down | -0.1257105364 |
| GSE37065 | Down | -0.1087567394 |
| GSE28863_A1 | Down | -0.1224844067 |
| GSE28863_A2 | Down | -0.0652046797 |
| GSE28863_A3 | Down | -0.1678780774 |
| GSE28863_A4 | Up | 0.0992342342 |
| GSE48662 | Up | 0.1622190418 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035993 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038601 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-345-5p | MIMAT0000772 | MIRT042729 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
