HCSGD entry for VPS45
1. General information
| Official gene symbol | VPS45 |
|---|---|
| Entrez ID | 11311 |
| Gene full name | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| Other gene symbols | H1 H1VPS45 VPS45A VPS45B VPS54A VSP45 VSP45A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0006886 | Intracellular protein transport | NAS | biological_process |
| GO:0006904 | Vesicle docking involved in exocytosis | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9468351886 | 0.0748152844 | 0.9999902473 | 0.5159059733 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0230384623 |
| GSE13712_SHEAR | Up | 0.0468800314 |
| GSE13712_STATIC | Down | -0.1610364715 |
| GSE19018 | Up | 0.0250612137 |
| GSE19899_A1 | Down | -0.4312533453 |
| GSE19899_A2 | Down | -0.2524173668 |
| PubMed_21979375_A1 | Down | -0.3867511689 |
| PubMed_21979375_A2 | Down | -0.2394295082 |
| GSE35957 | Down | -0.0148659156 |
| GSE36640 | Up | 0.1437786194 |
| GSE54402 | Down | -0.0958802115 |
| GSE9593 | Up | 0.0338901446 |
| GSE43922 | Down | -0.1900556205 |
| GSE24585 | Up | 0.5996055566 |
| GSE37065 | Up | 0.0154000476 |
| GSE28863_A1 | Down | -0.1219239877 |
| GSE28863_A2 | Up | 0.1868627495 |
| GSE28863_A3 | Down | -0.7864134575 |
| GSE28863_A4 | Down | -0.2843956405 |
| GSE48662 | Down | -0.3120695718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | MIRT003873 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT004367 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025396 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045187 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048519 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048645 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
