HCSGD entry for PLCD3
1. General information
| Official gene symbol | PLCD3 |
|---|---|
| Entrez ID | 113026 |
| Gene full name | phospholipase C, delta 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0004435 | Phosphatidylinositol phospholipase C activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0042127 | Regulation of cell proliferation | IEA | biological_process |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0060716 | Labyrinthine layer blood vessel development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2121882641 | 0.5892274458 | 0.8878723573 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0289343784 |
| GSE13712_SHEAR | Down | -0.8034330623 |
| GSE13712_STATIC | Down | -0.0184540133 |
| GSE19018 | Down | -0.0664407041 |
| GSE19899_A1 | Down | -0.1621023144 |
| GSE19899_A2 | Down | -0.0098181254 |
| PubMed_21979375_A1 | Down | -0.2510508152 |
| PubMed_21979375_A2 | Up | 0.1547997107 |
| GSE35957 | Up | 0.4945528181 |
| GSE36640 | Up | 0.4979707136 |
| GSE54402 | Down | -0.1953739952 |
| GSE9593 | Up | 0.2565773262 |
| GSE43922 | Down | -0.0856399703 |
| GSE24585 | Up | 0.1045295368 |
| GSE37065 | Down | -0.1454523874 |
| GSE28863_A1 | Up | 0.2771650787 |
| GSE28863_A2 | Up | 0.1061870128 |
| GSE28863_A3 | Up | 0.4756501270 |
| GSE28863_A4 | Up | 0.0910018545 |
| GSE48662 | Up | 0.2251739243 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018736 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-320a | MIMAT0000510 | MIRT044610 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
