HCSGD entry for HOGA1
1. General information
| Official gene symbol | HOGA1 |
|---|---|
| Entrez ID | 112817 |
| Gene full name | 4-hydroxy-2-oxoglutarate aldolase 1 |
| Other gene symbols | C10orf65 DHDPS2 DHDPSL HP3 NPL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0008700 | 4-hydroxy-2-oxoglutarate aldolase activity | IDA ISS | molecular_function |
| GO:0009436 | Glyoxylate catabolic process | IMP | biological_process |
| GO:0016829 | Lyase activity | IEA | molecular_function |
| GO:0019470 | 4-hydroxyproline catabolic process | IDA | biological_process |
| GO:0033609 | Oxalate metabolic process | IMP | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0042866 | Pyruvate biosynthetic process | IDA | biological_process |
| GO:0046487 | Glyoxylate metabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3931340527 | 0.7637797272 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0038667916 |
| GSE13712_SHEAR | Up | 0.4186123009 |
| GSE13712_STATIC | Up | 0.2687609389 |
| GSE19018 | Up | 0.0680417804 |
| GSE19899_A1 | Up | 0.0801851042 |
| GSE19899_A2 | Down | -0.0584919255 |
| PubMed_21979375_A1 | Up | 0.3411472578 |
| PubMed_21979375_A2 | Down | -0.1885226596 |
| GSE35957 | Down | -0.1161978453 |
| GSE36640 | Down | -0.0580380518 |
| GSE54402 | Up | 0.1255166557 |
| GSE9593 | Down | -0.0248502418 |
| GSE43922 | Up | 0.0133659353 |
| GSE24585 | Up | 0.3525889011 |
| GSE37065 | Down | -0.0942543114 |
| GSE28863_A1 | Down | -0.0657492305 |
| GSE28863_A2 | Down | -0.1160541457 |
| GSE28863_A3 | Up | 0.3216675237 |
| GSE28863_A4 | Down | -0.0457680072 |
| GSE48662 | Down | -0.0250122299 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049270 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
