HCSGD entry for ATXN2L
1. General information
| Official gene symbol | ATXN2L |
|---|---|
| Entrez ID | 11273 |
| Gene full name | ataxin 2-like |
| Other gene symbols | A2D A2LG A2LP A2RP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0010494 | Cytoplasmic stress granule | IDA | cellular_component |
| GO:0010603 | Regulation of cytoplasmic mRNA processing body assembly | IDA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0034063 | Stress granule assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3903984499 | 0.8329636412 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0521091629 |
| GSE13712_SHEAR | Up | 0.2866272201 |
| GSE13712_STATIC | Down | -0.0799056097 |
| GSE19018 | Up | 0.0168116259 |
| GSE19899_A1 | Up | 0.0138993436 |
| GSE19899_A2 | Up | 0.2735738045 |
| PubMed_21979375_A1 | Up | 0.0806849315 |
| PubMed_21979375_A2 | Down | -0.0912684270 |
| GSE35957 | Up | 0.0934401724 |
| GSE36640 | Down | -0.2615529455 |
| GSE54402 | Up | 0.1602325195 |
| GSE9593 | Up | 0.0651683877 |
| GSE43922 | Up | 0.2741182510 |
| GSE24585 | Down | -0.0284913657 |
| GSE37065 | Down | -0.1296152190 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1560027217 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023136 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025212 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030105 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031977 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031977 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036019 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036758 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037491 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039381 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040952 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042988 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043087 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043652 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049467 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051389 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051554 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051974 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052632 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
