HCSGD entry for PDCD10
1. General information
| Official gene symbol | PDCD10 |
|---|---|
| Entrez ID | 11235 |
| Gene full name | programmed cell death 10 |
| Other gene symbols | CCM3 TFAR15 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
| GO:0043406 | Positive regulation of MAP kinase activity | IDA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3687046389 | 0.4318294290 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1436402724 |
| GSE13712_SHEAR | Up | 0.3309533147 |
| GSE13712_STATIC | Up | 0.2079692027 |
| GSE19018 | Down | -0.1267315087 |
| GSE19899_A1 | Up | 0.1440141718 |
| GSE19899_A2 | Up | 0.1983795443 |
| PubMed_21979375_A1 | Up | 0.5302267565 |
| PubMed_21979375_A2 | Up | 0.3653997472 |
| GSE35957 | Down | -0.2254395419 |
| GSE36640 | Down | -0.0507308727 |
| GSE54402 | Up | 0.2542134838 |
| GSE9593 | Down | -0.1120834830 |
| GSE43922 | Up | 0.2534860866 |
| GSE24585 | Up | 0.0139240674 |
| GSE37065 | Up | 0.2139601365 |
| GSE28863_A1 | Down | -0.1838852879 |
| GSE28863_A2 | Up | 0.1899036909 |
| GSE28863_A3 | Down | -0.5840438237 |
| GSE28863_A4 | Down | -0.2406835009 |
| GSE48662 | Down | -0.5883328932 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020819 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023428 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023815 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023815 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028601 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032330 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
