HCSGD entry for SEC63
1. General information
| Official gene symbol | SEC63 |
|---|---|
| Entrez ID | 11231 |
| Gene full name | SEC63 homolog (S. cerevisiae) |
| Other gene symbols | DNAJC23 ERdj2 PRO2507 SEC63L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006612 | Protein targeting to membrane | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | IMP | biological_process |
| GO:0006620 | Posttranslational protein targeting to membrane | IMP | biological_process |
| GO:0006807 | Nitrogen compound metabolic process | IEA | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0010259 | Multicellular organismal aging | IEA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031204 | Posttranslational protein targeting to membrane, translocation | IEA | biological_process |
| GO:0072001 | Renal system development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6312993085 | 0.2177453934 | 0.9999902473 | 0.8983192006 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0362446203 |
| GSE13712_SHEAR | Down | -0.1398661401 |
| GSE13712_STATIC | Down | -0.1743006641 |
| GSE19018 | Down | -0.2812959596 |
| GSE19899_A1 | Down | -0.0088017235 |
| GSE19899_A2 | Down | -0.3913368731 |
| PubMed_21979375_A1 | Down | -0.5162950925 |
| PubMed_21979375_A2 | Down | -0.2893264305 |
| GSE35957 | Up | 0.3636474353 |
| GSE36640 | Up | 0.9342136811 |
| GSE54402 | Down | -0.4091430892 |
| GSE9593 | Up | 0.1942038775 |
| GSE43922 | Up | 0.1420912399 |
| GSE24585 | Up | 0.0321387019 |
| GSE37065 | Down | -0.0888186135 |
| GSE28863_A1 | Up | 0.0451006969 |
| GSE28863_A2 | Up | 0.3149909897 |
| GSE28863_A3 | Down | -0.1943009939 |
| GSE28863_A4 | Down | -0.0023894333 |
| GSE48662 | Down | -0.1284664599 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026665 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030915 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038508 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038691 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051342 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
