HCSGD entry for DDX20

1. General information

Official gene symbolDDX20
Entrez ID11218
Gene full nameDEAD (Asp-Glu-Ala-Asp) box polypeptide 20
Other gene symbolsDP103 GEMIN3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000244Spliceosomal tri-snRNP complex assemblyTASbiological_process
GO:0000387Spliceosomal snRNP assemblyIDA TASbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0004004ATP-dependent RNA helicase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005681Spliceosomal complexIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006396RNA processingTASbiological_process
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0017053Transcriptional repressor complexIEAcellular_component
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0032797SMN complexIDAcellular_component
GO:0034660NcRNA metabolic processTASbiological_process
GO:0034719SMN-Sm protein complexIDAcellular_component
GO:0043065Positive regulation of apoptotic processIGI ISSbiological_process
GO:0048477OogenesisIEAbiological_process
GO:0050810Regulation of steroid biosynthetic processIEAbiological_process
GO:0097504Gemini of coiled bodiesIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68885429880.17244219820.99999024730.8042068520

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0767167439
GSE13712_SHEARUp0.1453107967
GSE13712_STATICUp0.1657219049
GSE19018Down-0.4392006469
GSE19899_A1Down-0.0172176507
GSE19899_A2Up0.1028428313
PubMed_21979375_A1Up0.6642138690
PubMed_21979375_A2Up0.1693695242
GSE35957Down-0.3311961237
GSE36640Down-0.4253903613
GSE54402Up0.2122832189
GSE9593Up0.2395509722
GSE43922Down-0.0087091989
GSE24585Down-0.2026212553
GSE37065Up0.1772494629
GSE28863_A1Down-0.5145370937
GSE28863_A2Up0.2601478819
GSE28863_A3Down-0.4961837747
GSE28863_A4Down-0.1635977285
GSE48662Down-0.3472555483

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039368CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043191CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051902CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.