HCSGD entry for CHM
1. General information
| Official gene symbol | CHM |
|---|---|
| Entrez ID | 1121 |
| Gene full name | choroideremia (Rab escort protein 1) |
| Other gene symbols | DXS540 GGTA HSD-32 REP-1 TCD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001568 | Blood vessel development | IEA | biological_process |
| GO:0004663 | Rab geranylgeranyltransferase activity | IEA | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005829 | Cytosol | IMP | cellular_component |
| GO:0005968 | Rab-protein geranylgeranyltransferase complex | IDA IEA | cellular_component |
| GO:0006612 | Protein targeting to membrane | IMP | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0017137 | Rab GTPase binding | IDA IPI | molecular_function |
| GO:0018344 | Protein geranylgeranylation | IDA | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0140841153 | 0.9339970670 | 0.2942400476 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0704276707 |
| GSE13712_SHEAR | Up | 0.4156892593 |
| GSE13712_STATIC | Up | 0.2110189277 |
| GSE19018 | Down | -0.1045471015 |
| GSE19899_A1 | Up | 0.3560830697 |
| GSE19899_A2 | Up | 0.5562279420 |
| PubMed_21979375_A1 | Up | 1.7377416406 |
| PubMed_21979375_A2 | Up | 0.7023891365 |
| GSE35957 | Up | 0.3776708364 |
| GSE36640 | Down | -0.3614836661 |
| GSE54402 | Up | 0.7025857945 |
| GSE9593 | Up | 0.2679674123 |
| GSE43922 | Up | 0.4372695699 |
| GSE24585 | Up | 0.5078566361 |
| GSE37065 | Up | 0.1807152742 |
| GSE28863_A1 | Down | -0.1295241230 |
| GSE28863_A2 | Up | 0.1203701787 |
| GSE28863_A3 | Down | -0.7696205303 |
| GSE28863_A4 | Up | 0.1144250194 |
| GSE48662 | Down | -0.3490202665 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024694 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026666 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029824 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
