HCSGD entry for ABCB8

1. General information

Official gene symbolABCB8
Entrez ID11194
Gene full nameATP-binding cassette, sub-family B (MDR/TAP), member 8
Other gene symbolsEST328128 M-ABC1 MABC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005740Mitochondrial envelopeTAScellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0006200ATP catabolic processIBAbiological_process
GO:0006810TransportTASbiological_process
GO:0008152Metabolic processIBAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIBA IEAcellular_component
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIBA IEAmolecular_function
GO:0043190ATP-binding cassette (ABC) transporter complexTAScellular_component
GO:0055085Transmembrane transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28215276780.92240597240.97972267511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0490991287
GSE13712_SHEARUp0.1054478661
GSE13712_STATICUp0.0692010922
GSE19018Down-0.0519369360
GSE19899_A1Up0.0375510646
GSE19899_A2Down-0.2730104459
PubMed_21979375_A1Up0.6272344663
PubMed_21979375_A2Up0.4183330906
GSE35957Down-0.0678147639
GSE36640Up0.2366892586
GSE54402Up0.0365963333
GSE9593Down-0.0649919919
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0017877813
GSE28863_A2Up0.3873721923
GSE28863_A3Up0.1841698131
GSE28863_A4Down-0.0008616432
GSE48662Up0.2060739932

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT051898CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.