HCSGD entry for CEP250
1. General information
| Official gene symbol | CEP250 |
|---|---|
| Entrez ID | 11190 |
| Gene full name | centrosomal protein 250kDa |
| Other gene symbols | C-NAP1 CEP2 CNAP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | IDA TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005814 | Centriole | IDA IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | NAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005929 | Cilium | IEA | cellular_component |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0008104 | Protein localization | IMP | biological_process |
| GO:0010457 | Centriole-centriole cohesion | IMP | biological_process |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0030997 | Regulation of centriole-centriole cohesion | IDA | biological_process |
| GO:0031616 | Spindle pole centrosome | IEA | cellular_component |
| GO:0043234 | Protein complex | IMP | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4434500665 | 0.5319471373 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1705122634 |
| GSE13712_SHEAR | Up | 0.1436627862 |
| GSE13712_STATIC | Up | 0.0447817345 |
| GSE19018 | Up | 0.3640593339 |
| GSE19899_A1 | Down | -0.0054694257 |
| GSE19899_A2 | Up | 0.2839093759 |
| PubMed_21979375_A1 | Up | 0.2897740390 |
| PubMed_21979375_A2 | Up | 0.3590466808 |
| GSE35957 | Down | -0.1357027575 |
| GSE36640 | Down | -0.8673551436 |
| GSE54402 | Up | 0.0449909951 |
| GSE9593 | Up | 0.1140960110 |
| GSE43922 | Up | 0.0401599182 |
| GSE24585 | Down | -0.1125509404 |
| GSE37065 | Down | -0.1015755343 |
| GSE28863_A1 | Up | 0.2842158862 |
| GSE28863_A2 | Down | -0.3969092568 |
| GSE28863_A3 | Up | 0.2092811104 |
| GSE28863_A4 | Down | -0.1213860931 |
| GSE48662 | Up | 0.0522501598 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040255 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042169 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046692 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
