HCSGD entry for MAP4K1
1. General information
| Official gene symbol | MAP4K1 |
|---|---|
| Entrez ID | 11184 |
| Gene full name | mitogen-activated protein kinase kinase kinase kinase 1 |
| Other gene symbols | HPK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000185 | Activation of MAPKKK activity | IC | biological_process |
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006950 | Response to stress | IDA | biological_process |
| GO:0007257 | Activation of JUN kinase activity | TAS | biological_process |
| GO:0008349 | MAP kinase kinase kinase kinase activity | IDA | molecular_function |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0018105 | Peptidyl-serine phosphorylation | IDA | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7150030850 | 0.5480097527 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0250997181 |
| GSE13712_SHEAR | Up | 0.0859382898 |
| GSE13712_STATIC | Up | 0.1402796696 |
| GSE19018 | Up | 0.1264867991 |
| GSE19899_A1 | Up | 0.0255505084 |
| GSE19899_A2 | Up | 0.0405817042 |
| PubMed_21979375_A1 | Down | -0.0651711920 |
| PubMed_21979375_A2 | Up | 0.0128816822 |
| GSE35957 | Up | 0.1035231852 |
| GSE36640 | Up | 0.0513845583 |
| GSE54402 | Down | -0.0663417413 |
| GSE9593 | Up | 0.0385462576 |
| GSE43922 | Up | 0.0842444735 |
| GSE24585 | Down | -0.0934200737 |
| GSE37065 | Down | -0.1543646504 |
| GSE28863_A1 | Down | -0.3882765199 |
| GSE28863_A2 | Down | -0.4103453442 |
| GSE28863_A3 | Up | 0.4277455858 |
| GSE28863_A4 | Up | 0.1054694955 |
| GSE48662 | Down | -0.1068623308 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
