HCSGD entry for FSTL1
1. General information
| Official gene symbol | FSTL1 |
|---|---|
| Entrez ID | 11167 |
| Gene full name | follistatin-like 1 |
| Other gene symbols | FRP FSL1 MIR198 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0030509 | BMP signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9709962159 | 0.0072392804 | 0.9999902473 | 0.1699777877 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4594298341 |
| GSE13712_SHEAR | Down | -0.3142716057 |
| GSE13712_STATIC | Up | 0.2076928588 |
| GSE19018 | Down | -0.4359167124 |
| GSE19899_A1 | Down | -0.5352243649 |
| GSE19899_A2 | Down | -1.6433338033 |
| PubMed_21979375_A1 | Down | -0.2582697398 |
| PubMed_21979375_A2 | Down | -1.3134739609 |
| GSE35957 | Down | -0.1679375065 |
| GSE36640 | Up | 0.3850382545 |
| GSE54402 | Down | -0.7325643911 |
| GSE9593 | Down | -0.3725176812 |
| GSE43922 | Down | -0.6640879671 |
| GSE24585 | Up | 0.6735413263 |
| GSE37065 | Down | -0.2340917151 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2107329233 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-206 | MIMAT0000462 | MIRT001789 | Reporter assay | Functional MTI | 17030984 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020891 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022846 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029771 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040347 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045682 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051922 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23466301 | These genes, PDIA3, WDR1, FSTL1, COPG1, LMAN1, and PDIA6, significantly downregulated |
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