HCSGD entry for LSM6

1. General information

Official gene symbolLSM6
Entrez ID11157
Gene full nameLSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Other gene symbolsYDR378C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000288Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005681Spliceosomal complexIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006364RRNA processingIEAbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0008033TRNA processingIEAbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0030532Small nuclear ribonucleoprotein complexTAScellular_component
GO:0043928Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98387170700.01090257970.99999024730.2064739568

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1727356720
GSE13712_SHEARUp0.0248490506
GSE13712_STATICUp0.0370953849
GSE19018Down-0.2193383602
GSE19899_A1Down-0.6525005432
GSE19899_A2Down-0.7012086527
PubMed_21979375_A1Down-1.3628786342
PubMed_21979375_A2Down-0.8954653480
GSE35957Down-0.5896338591
GSE36640Down-1.6285333184
GSE54402Down-0.0324496286
GSE9593Down-0.5701267863
GSE43922Down-0.2748970005
GSE24585Down-0.0667427932
GSE37065Up0.3665019253
GSE28863_A1Up0.1021787881
GSE28863_A2Up0.0297004521
GSE28863_A3Down-0.2510468706
GSE28863_A4Down-0.1550981324
GSE48662Down-0.0307756211

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

UridineDB02745 EXPT03205
Uridine-5'-MonophosphateDB03685 EXPT03155
Citric AcidDB04272 EXPT00922

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT032421ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.