HCSGD entry for CDC42EP1
1. General information
| Official gene symbol | CDC42EP1 |
|---|---|
| Entrez ID | 11135 |
| Gene full name | CDC42 effector protein (Rho GTPase binding) 1 |
| Other gene symbols | BORG5 CEP1 MSE55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007266 | Rho protein signal transduction | IEA | biological_process |
| GO:0008360 | Regulation of cell shape | IDA | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0031274 | Positive regulation of pseudopodium assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1743894799 | 0.0361673303 | 0.8196880357 | 0.3581466717 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3518146686 |
| GSE13712_SHEAR | Up | 0.3167435845 |
| GSE13712_STATIC | Down | -0.1664721952 |
| GSE19018 | Down | -0.3349846723 |
| GSE19899_A1 | Down | -0.2048132084 |
| GSE19899_A2 | Up | 0.6164624110 |
| PubMed_21979375_A1 | Up | 1.1953848809 |
| PubMed_21979375_A2 | Up | 2.3861611701 |
| GSE35957 | Up | 0.1700650532 |
| GSE36640 | Down | -0.5903272482 |
| GSE54402 | Down | -0.0636062321 |
| GSE9593 | Down | -0.2061249009 |
| GSE43922 | Up | 0.0493609351 |
| GSE24585 | Down | -0.8412386236 |
| GSE37065 | Down | -0.7655374482 |
| GSE28863_A1 | Down | -0.0182789129 |
| GSE28863_A2 | Down | -0.3738856209 |
| GSE28863_A3 | Up | 0.1791765830 |
| GSE28863_A4 | Down | -0.1240796249 |
| GSE48662 | Up | 0.1693828106 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1224-3p | MIMAT0005459 | MIRT036551 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037123 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039539 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039933 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043823 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
