HCSGD entry for CAPN10

1. General information

Official gene symbolCAPN10
Entrez ID11132
Gene full namecalpain 10
Other gene symbolsCANP10 NIDDM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000149SNARE bindingISSmolecular_function
GO:0004198Calcium-dependent cysteine-type endopeptidase activityIEA IMPmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005623CellIDAcellular_component
GO:0005829CytosolISScellular_component
GO:0005886Plasma membraneISScellular_component
GO:0006508ProteolysisIEA IMPbiological_process
GO:0008092Cytoskeletal protein bindingISSmolecular_function
GO:0031532Actin cytoskeleton reorganizationISSbiological_process
GO:0032024Positive regulation of insulin secretionIMPbiological_process
GO:0032388Positive regulation of intracellular transportISSbiological_process
GO:0032869Cellular response to insulin stimulusIMPbiological_process
GO:0046326Positive regulation of glucose importIMPbiological_process
GO:0097050Type B pancreatic cell apoptotic processIDAbiological_process
GO:0097194Execution phase of apoptosisIDAbiological_process
GO:2000676Positive regulation of type B pancreatic cell apoptotic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55138990540.90378799440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0411872524
GSE13712_SHEARDown-0.0467293955
GSE13712_STATICDown-0.1139357204
GSE19018Down-0.0116429734
GSE19899_A1Up0.0261765013
GSE19899_A2Up0.2319437945
PubMed_21979375_A1Up0.3543599162
PubMed_21979375_A2Up0.6049463064
GSE35957Down-0.1083600213
GSE36640Up0.0540532559
GSE54402Up0.0925983999
GSE9593Down-0.0425215514
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0126734209
GSE28863_A2Up0.1269821865
GSE28863_A3Up0.0650554036
GSE28863_A4Up0.0283326678
GSE48662Up0.0730960013

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.