HCSGD entry for PTPRT
1. General information
| Official gene symbol | PTPRT |
|---|---|
| Entrez ID | 11122 |
| Gene full name | protein tyrosine phosphatase, receptor type, T |
| Other gene symbols | RPTPrho |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IDA | biological_process |
| GO:0007155 | Cell adhesion | NAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IDA | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | IMP | biological_process |
| GO:0008013 | Beta-catenin binding | IPI | molecular_function |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016790 | Thiolester hydrolase activity | IEA | molecular_function |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IMP | biological_process |
| GO:0045294 | Alpha-catenin binding | IDA | molecular_function |
| GO:0045295 | Gamma-catenin binding | IDA | molecular_function |
| GO:0045296 | Cadherin binding | IPI | molecular_function |
| GO:0051393 | Alpha-actinin binding | IEA | molecular_function |
| GO:0070097 | Delta-catenin binding | IPI | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6422557806 | 0.8546743589 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0181029233 |
| GSE13712_SHEAR | Down | -0.0035709157 |
| GSE13712_STATIC | Down | -0.1131020185 |
| GSE19018 | Down | -0.0524604029 |
| GSE19899_A1 | Up | 0.2561440580 |
| GSE19899_A2 | Up | 0.0385915375 |
| PubMed_21979375_A1 | Up | 0.2093344249 |
| PubMed_21979375_A2 | Down | -0.0149701062 |
| GSE35957 | Up | 0.1643343291 |
| GSE36640 | Down | -0.1372509921 |
| GSE54402 | Up | 0.1951685343 |
| GSE9593 | Up | 0.0799089110 |
| GSE43922 | Down | -0.0242271564 |
| GSE24585 | Up | 0.0335303010 |
| GSE37065 | Up | 0.0089053244 |
| GSE28863_A1 | Down | -0.0443511936 |
| GSE28863_A2 | Down | -0.0058808746 |
| GSE28863_A3 | Up | 0.2337882089 |
| GSE28863_A4 | Up | 0.0554139720 |
| GSE48662 | Down | -0.1341590004 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017080 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043524 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047447 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047550 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051085 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3928-3p | MIMAT0018205 | MIRT052887 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 14499637 | Concomitantly, we also discovered an increase in expression of receptor protein tyrosine phosphatase alpha (RPTPalpha) |
Entries Per Page
Displaying Page of
