HCSGD entry for PTPN21
1. General information
| Official gene symbol | PTPN21 |
|---|---|
| Entrez ID | 11099 |
| Gene full name | protein tyrosine phosphatase, non-receptor type 21 |
| Other gene symbols | PTPD1 PTPRL10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1526310019 | 0.5445689222 | 0.7798500872 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0364449782 |
| GSE13712_SHEAR | Up | 0.5918408150 |
| GSE13712_STATIC | Up | 0.1550476207 |
| GSE19018 | Down | -0.2923444444 |
| GSE19899_A1 | Down | -0.2064314959 |
| GSE19899_A2 | Down | -0.2146822881 |
| PubMed_21979375_A1 | Down | -0.2070759216 |
| PubMed_21979375_A2 | Up | 0.1371037993 |
| GSE35957 | Up | 0.5226209321 |
| GSE36640 | Up | 0.2663757520 |
| GSE54402 | Down | -0.1283744907 |
| GSE9593 | Up | 0.2610915501 |
| GSE43922 | Down | -0.2398862500 |
| GSE24585 | Down | -0.2053570426 |
| GSE37065 | Down | -0.1647923002 |
| GSE28863_A1 | Up | 0.7111952481 |
| GSE28863_A2 | Up | 0.7185869756 |
| GSE28863_A3 | Up | 0.0463988672 |
| GSE28863_A4 | Down | -0.0412142158 |
| GSE48662 | Up | 0.3510123900 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040133 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
