HCSGD entry for PRSS23
1. General information
| Official gene symbol | PRSS23 |
|---|---|
| Entrez ID | 11098 |
| Gene full name | protease, serine, 23 |
| Other gene symbols | SIG13 SPUVE ZSIG13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0314256905 | 0.0451297329 | 0.4099809312 | 0.3991464046 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2974061197 |
| GSE13712_SHEAR | Down | -0.3223742900 |
| GSE13712_STATIC | Up | 0.3947828923 |
| GSE19018 | Up | 0.7294191047 |
| GSE19899_A1 | Up | 0.7967454291 |
| GSE19899_A2 | Down | -0.7748285169 |
| PubMed_21979375_A1 | Down | -1.6628114557 |
| PubMed_21979375_A2 | Up | 0.4087626825 |
| GSE35957 | Up | 0.0088563762 |
| GSE36640 | Up | 1.7508388822 |
| GSE54402 | Down | -0.6516146881 |
| GSE9593 | Up | 1.2247562789 |
| GSE43922 | Down | -0.0788524067 |
| GSE24585 | Down | -1.2462461314 |
| GSE37065 | Up | 0.0631897023 |
| GSE28863_A1 | Down | -0.0746895976 |
| GSE28863_A2 | Up | 0.1012496593 |
| GSE28863_A3 | Down | -0.2795930624 |
| GSE28863_A4 | Up | 0.1637040660 |
| GSE48662 | Up | 0.2450519425 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024605 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026709 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
