HCSGD entry for KERA
1. General information
| Official gene symbol | KERA |
|---|---|
| Entrez ID | 11081 |
| Gene full name | keratocan |
| Other gene symbols | CNA2 SLRR2B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | NAS | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0018146 | Keratan sulfate biosynthetic process | TAS | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0042339 | Keratan sulfate metabolic process | TAS | biological_process |
| GO:0042340 | Keratan sulfate catabolic process | TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
| GO:0061303 | Cornea development in camera-type eye | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1817737700 | 0.9133798982 | 0.8355688788 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3945983559 |
| GSE13712_SHEAR | Down | -0.0200662699 |
| GSE13712_STATIC | Up | 0.1711730134 |
| GSE19018 | Up | 0.2591315579 |
| GSE19899_A1 | Up | 0.3069266229 |
| GSE19899_A2 | Down | -0.0872519256 |
| PubMed_21979375_A1 | Up | 0.0693130521 |
| PubMed_21979375_A2 | Up | 0.2568576101 |
| GSE35957 | Up | 0.2220996901 |
| GSE36640 | Up | 0.1357467569 |
| GSE54402 | Up | 0.0750218479 |
| GSE9593 | Down | -0.1845251380 |
| GSE43922 | Up | 0.0133152163 |
| GSE24585 | Down | -0.1121536397 |
| GSE37065 | Down | -0.0287704676 |
| GSE28863_A1 | Up | 0.0177440745 |
| GSE28863_A2 | Up | 0.0598100945 |
| GSE28863_A3 | Up | 0.3072854859 |
| GSE28863_A4 | Down | -0.0776022383 |
| GSE48662 | Up | 0.0884262006 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018215 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11344338 | The MK/T-1 cells express vimentin, tubulin, lumican, mimecan, decorin and collagen I, but not keratocan |
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