HCSGD entry for CPSF6
1. General information
| Official gene symbol | CPSF6 |
|---|---|
| Entrez ID | 11052 |
| Gene full name | cleavage and polyadenylation specific factor 6, 68kDa |
| Other gene symbols | CFIM CFIM68 HPBRII-4 HPBRII-7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0003729 | MRNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005849 | MRNA cleavage factor complex | IDA | cellular_component |
| GO:0006378 | MRNA polyadenylation | IMP | biological_process |
| GO:0006397 | MRNA processing | IDA | biological_process |
| GO:0030529 | Ribonucleoprotein complex | IDA | cellular_component |
| GO:0042382 | Paraspeckles | IDA | cellular_component |
| GO:0051262 | Protein tetramerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9831271646 | 0.0107091486 | 0.9999902473 | 0.2050003636 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2465693481 |
| GSE13712_SHEAR | Down | -0.2309626451 |
| GSE13712_STATIC | Down | -0.1493546190 |
| GSE19018 | Down | -0.3890970419 |
| GSE19899_A1 | Down | -0.1129204101 |
| GSE19899_A2 | Down | -1.2573224154 |
| PubMed_21979375_A1 | Down | -0.3960784099 |
| PubMed_21979375_A2 | Down | -0.7981978651 |
| GSE35957 | Down | -0.6689660833 |
| GSE36640 | Down | -1.1797844379 |
| GSE54402 | Up | 0.1603768902 |
| GSE9593 | Down | -0.6507135930 |
| GSE43922 | Up | 0.0073667716 |
| GSE24585 | Down | -0.0344448859 |
| GSE37065 | Down | -0.1753055634 |
| GSE28863_A1 | Up | 0.4130379357 |
| GSE28863_A2 | Up | 0.1767524797 |
| GSE28863_A3 | Down | -0.6977827835 |
| GSE28863_A4 | Up | 0.2066926724 |
| GSE48662 | Down | -0.5737945714 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024266 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026674 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049065 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
