HCSGD entry for RAB35
1. General information
| Official gene symbol | RAB35 |
|---|---|
| Entrez ID | 11021 |
| Gene full name | RAB35, member RAS oncogene family |
| Other gene symbols | H-ray RAB1C RAY |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA IEA | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | IDA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005905 | Coated pit | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008104 | Protein localization | IMP | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0010008 | Endosome membrane | ISS | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016197 | Endosomal transport | IMP | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0031175 | Neuron projection development | ISS | biological_process |
| GO:0031253 | Cell projection membrane | IDA | cellular_component |
| GO:0036010 | Protein localization to endosome | IMP | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0045171 | Intercellular bridge | IDA | cellular_component |
| GO:0045334 | Clathrin-coated endocytic vesicle | IDA | cellular_component |
| GO:1990090 | Cellular response to nerve growth factor stimulus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3253552449 | 0.5017261578 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0269750480 |
| GSE13712_SHEAR | Up | 0.3861755730 |
| GSE13712_STATIC | Up | 0.2120556698 |
| GSE19018 | Down | -0.0970199714 |
| GSE19899_A1 | Down | -0.1530414867 |
| GSE19899_A2 | Up | 0.5383499038 |
| PubMed_21979375_A1 | Up | 0.9812725712 |
| PubMed_21979375_A2 | Down | -0.4918766922 |
| GSE35957 | Up | 0.4127535905 |
| GSE36640 | Down | -0.2694047906 |
| GSE54402 | Up | 0.2941466060 |
| GSE9593 | Up | 0.0389704954 |
| GSE43922 | Up | 0.0855406233 |
| GSE24585 | Down | -0.1084530947 |
| GSE37065 | Down | -0.1445231420 |
| GSE28863_A1 | Down | -0.1609678628 |
| GSE28863_A2 | Down | -0.0562310055 |
| GSE28863_A3 | Down | -0.5651617643 |
| GSE28863_A4 | Up | 0.1156597281 |
| GSE48662 | Down | -0.0169453161 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-760 | MIMAT0004957 | MIRT036789 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041316 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047800 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
