HCSGD entry for KDELR2
1. General information
| Official gene symbol | KDELR2 |
|---|---|
| Entrez ID | 11014 |
| Gene full name | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| Other gene symbols | ELP-1 ERD2.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005046 | KDEL sequence binding | TAS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0005801 | Cis-Golgi network | IEA | cellular_component |
| GO:0006621 | Protein retention in ER lumen | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0046923 | ER retention sequence binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9932808670 | 0.0038653851 | 0.9999902473 | 0.1265432836 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1746113260 |
| GSE13712_SHEAR | Down | -0.0906735776 |
| GSE13712_STATIC | Down | -0.0256690907 |
| GSE19018 | Up | 0.1336771477 |
| GSE19899_A1 | Down | -0.5254859138 |
| GSE19899_A2 | Down | -0.4546623340 |
| PubMed_21979375_A1 | Down | -0.8229001080 |
| PubMed_21979375_A2 | Down | -0.5448254483 |
| GSE35957 | Down | -0.0750873824 |
| GSE36640 | Up | 0.2677814535 |
| GSE54402 | Down | -0.1993195652 |
| GSE9593 | Up | 0.0916954877 |
| GSE43922 | Down | -0.0165661288 |
| GSE24585 | Up | 0.0471352784 |
| GSE37065 | Down | -0.1606753243 |
| GSE28863_A1 | Down | -0.9559384738 |
| GSE28863_A2 | Down | -0.8104410784 |
| GSE28863_A3 | Down | -1.0095841808 |
| GSE28863_A4 | Down | -0.4443304315 |
| GSE48662 | Down | -0.5363739693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022164 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042919 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-301a-3p | MIMAT0000688 | MIRT044224 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048554 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-19a-3p | MIMAT0000073 | MIRT050641 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
