HCSGD entry for ASCC3
1. General information
| Official gene symbol | ASCC3 |
|---|---|
| Entrez ID | 10973 |
| Gene full name | activating signal cointegrator 1 complex subunit 3 |
| Other gene symbols | ASC1p200 DJ467N11.1 HELIC1 RNAH dJ121G13.4 p200 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006307 | DNA dealkylation involved in DNA repair | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008283 | Cell proliferation | IMP | biological_process |
| GO:0032508 | DNA duplex unwinding | IDA | biological_process |
| GO:0043140 | ATP-dependent 3'-5' DNA helicase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0236451009 | 0.7076462634 | 0.3651765396 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2205747347 |
| GSE13712_SHEAR | Up | 0.7534899350 |
| GSE13712_STATIC | Up | 0.8650942305 |
| GSE19018 | Up | 0.4208821847 |
| GSE19899_A1 | Up | 0.2132204798 |
| GSE19899_A2 | Up | 0.7264179205 |
| PubMed_21979375_A1 | Up | 0.3275071491 |
| PubMed_21979375_A2 | Up | 1.1005802436 |
| GSE35957 | Up | 0.1531046698 |
| GSE36640 | Up | 0.1352858906 |
| GSE54402 | Down | -0.2160667561 |
| GSE9593 | Down | -0.2515562503 |
| GSE43922 | Up | 0.2540406098 |
| GSE24585 | Up | 0.0710962307 |
| GSE37065 | Down | -0.0685043885 |
| GSE28863_A1 | Down | -0.1442358127 |
| GSE28863_A2 | Up | 0.1371369554 |
| GSE28863_A3 | Down | -0.9225492183 |
| GSE28863_A4 | Down | -0.1810552729 |
| GSE48662 | Up | 1.1141837828 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022461 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027593 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028510 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031604 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032308 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036492 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039333 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051396 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052581 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
