HCSGD entry for MLLT11
1. General information
| Official gene symbol | MLLT11 |
|---|---|
| Entrez ID | 10962 |
| Gene full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| Other gene symbols | AF1Q RP11-316M1.10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051901 | Positive regulation of mitochondrial depolarization | IDA | biological_process |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | IDA | biological_process |
| GO:0097191 | Extrinsic apoptotic signaling pathway | IDA | biological_process |
| GO:0097193 | Intrinsic apoptotic signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0045308347 | 0.2717844649 | 0.1782794074 | 0.9970228432 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.2553441565 |
| GSE13712_SHEAR | Up | 0.2937957656 |
| GSE13712_STATIC | Up | 0.3209131801 |
| GSE19018 | Up | 0.3415224335 |
| GSE19899_A1 | Up | 1.1698284841 |
| GSE19899_A2 | Up | 0.5400354233 |
| PubMed_21979375_A1 | Up | 0.3713192750 |
| PubMed_21979375_A2 | Up | 0.1491577808 |
| GSE35957 | Down | -0.7433518214 |
| GSE36640 | Up | 1.5262913413 |
| GSE54402 | Up | 1.0416962161 |
| GSE9593 | Up | 0.2795478653 |
| GSE43922 | Up | 0.5214110262 |
| GSE24585 | Up | 0.1555331948 |
| GSE37065 | Up | 0.2787264273 |
| GSE28863_A1 | Down | -1.3191036984 |
| GSE28863_A2 | Up | 0.1706918108 |
| GSE28863_A3 | Down | -1.8588496234 |
| GSE28863_A4 | Up | 0.0082690649 |
| GSE48662 | Down | -0.0301119550 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001441 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005154 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016055 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
