HCSGD entry for SEC61B

1. General information

Official gene symbolSEC61B
Entrez ID10952
Gene full nameSec61 beta subunit
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000060Protein import into nucleus, translocationIMPbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0006412TranslationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0030970Retrograde protein transport, ER to cytosolIMPbiological_process
GO:0031205Endoplasmic reticulum Sec complexISScellular_component
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0043022Ribosome bindingIEAmolecular_function
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0048408Epidermal growth factor bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78076600810.42368418750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0741716152
GSE13712_SHEARDown-0.0503629168
GSE13712_STATICDown-0.0812941489
GSE19018Down-0.2913818811
GSE19899_A1Up0.0469830202
GSE19899_A2Up0.0473446812
PubMed_21979375_A1Up0.1387218687
PubMed_21979375_A2Down-0.0040860874
GSE35957Down-0.1461133843
GSE36640Up0.0421188097
GSE54402Up0.3889351662
GSE9593Down-0.1522158774
GSE43922Down-0.1406568547
GSE24585Up0.3035316183
GSE37065Down-0.1726213992
GSE28863_A1Up0.1192882832
GSE28863_A2Up0.0668843572
GSE28863_A3Down-0.2052621391
GSE28863_A4Up0.1080497599
GSE48662Down-0.5409505227

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-133a-3pMIMAT0000427MIRT021708MicroarrayFunctional MTI (Weak)21396852
hsa-miR-324-5pMIMAT0000761MIRT043126CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.