HCSGD entry for RALBP1
1. General information
| Official gene symbol | RALBP1 |
|---|---|
| Entrez ID | 10928 |
| Gene full name | ralA binding protein 1 |
| Other gene symbols | RIP1 RLIP1 RLIP76 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006810 | Transport | IDA | biological_process |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IPI TAS | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016887 | ATPase activity | IDA | molecular_function |
| GO:0017160 | Ral GTPase binding | IEA IPI | molecular_function |
| GO:0030675 | Rac GTPase activator activity | IDA IEA | molecular_function |
| GO:0032855 | Positive regulation of Rac GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0043089 | Positive regulation of Cdc42 GTPase activity | IDA IEA | biological_process |
| GO:0043492 | ATPase activity, coupled to movement of substances | IDA | molecular_function |
| GO:0048365 | Rac GTPase binding | IPI | molecular_function |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0377506136 | 0.9679913605 | 0.4384968667 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1064807068 |
| GSE13712_SHEAR | Up | 0.1173661454 |
| GSE13712_STATIC | Up | 0.0392249585 |
| GSE19018 | Up | 0.5324304659 |
| GSE19899_A1 | Down | -0.1061927362 |
| GSE19899_A2 | Up | 0.5343075390 |
| PubMed_21979375_A1 | Up | 0.5847180080 |
| PubMed_21979375_A2 | Up | 0.3009478074 |
| GSE35957 | Up | 0.1602062940 |
| GSE36640 | Up | 0.1481276480 |
| GSE54402 | Down | -0.1352458505 |
| GSE9593 | Up | 0.3020978949 |
| GSE43922 | Up | 0.0071743288 |
| GSE24585 | Down | -0.1676518343 |
| GSE37065 | Down | -0.2011931275 |
| GSE28863_A1 | Up | 0.3947811598 |
| GSE28863_A2 | Up | 0.6536189376 |
| GSE28863_A3 | Up | 0.4427466574 |
| GSE28863_A4 | Up | 0.2232228267 |
| GSE48662 | Up | 0.4043288083 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1914-5p | MIMAT0007889 | MIRT035794 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040266 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045735 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047496 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047750 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
