HCSGD entry for FASTK
1. General information
| Official gene symbol | FASTK |
|---|---|
| Entrez ID | 10922 |
| Gene full name | Fas-activated serine/threonine kinase |
| Other gene symbols | FAST |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0033867 | Fas-activated serine/threonine kinase activity | IEA | molecular_function |
| GO:0043484 | Regulation of RNA splicing | IDA IMP | biological_process |
| GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9653614528 | 0.1383373808 | 0.9999902473 | 0.7162428009 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0857504739 |
| GSE13712_SHEAR | Down | -0.0042598861 |
| GSE13712_STATIC | Down | -0.0416994166 |
| GSE19018 | Down | -0.0981769400 |
| GSE19899_A1 | Down | -0.4062920991 |
| GSE19899_A2 | Down | -0.2062535306 |
| PubMed_21979375_A1 | Down | -0.3950891385 |
| PubMed_21979375_A2 | Down | -0.0185468979 |
| GSE35957 | Up | 0.1234111661 |
| GSE36640 | Up | 0.0614188090 |
| GSE54402 | Up | 0.0028123290 |
| GSE9593 | Down | -0.1023565503 |
| GSE43922 | Down | -0.0261796020 |
| GSE24585 | Up | 0.1454558165 |
| GSE37065 | Down | -0.3684889519 |
| GSE28863_A1 | Down | -0.0571067538 |
| GSE28863_A2 | Up | 0.0722792515 |
| GSE28863_A3 | Down | -0.1277768678 |
| GSE28863_A4 | Down | -0.2511002761 |
| GSE48662 | Down | -0.1808116303 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043485 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045322 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
