HCSGD entry for EDAR

1. General information

Official gene symbolEDAR
Entrez ID10913
Gene full nameectodysplasin A receptor
Other gene symbolsDL ECTD10A ECTD10B ED1R ED3 ED5 EDA-A1R EDA1R EDA3 HRM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001942Hair follicle developmentIEAbiological_process
GO:0004872Receptor activityIDAmolecular_function
GO:0004888Transmembrane signaling receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0008544Epidermis developmentTASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0042346Positive regulation of NF-kappaB import into nucleusIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0043473PigmentationIEAbiological_process
GO:0045177Apical part of cellIEAcellular_component
GO:0060662Salivary gland cavitationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24788686980.92681561110.93580387211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0243053369
GSE13712_SHEARUp0.1919851247
GSE13712_STATICUp0.1540310570
GSE19018Up0.1556247844
GSE19899_A1Up0.2529362395
GSE19899_A2Down-0.1511302865
PubMed_21979375_A1Down-0.0379094309
PubMed_21979375_A2Down-0.3786981855
GSE35957Up0.1038408635
GSE36640Up0.2188541537
GSE54402Up0.1001002769
GSE9593Up0.1014584737
GSE43922Up0.0129254757
GSE24585Up0.4192889461
GSE37065Up0.0234126982
GSE28863_A1Down-0.1112338226
GSE28863_A2Up0.1198154535
GSE28863_A3Up0.2916580438
GSE28863_A4Up0.1683623493
GSE48662Up0.0103210845

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.