HCSGD entry for DHRS4

1. General information

Official gene symbolDHRS4
Entrez ID10901
Gene full namedehydrogenase/reductase (SDR family) member 4
Other gene symbolsCR NRDR PHCR PSCD SCAD-SRL SDR-SRL SDR25C1 SDR25C2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00002533-keto sterol reductase activityIDAmolecular_function
GO:0004090Carbonyl reductase (NADPH) activityIDAmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005739MitochondrionISScellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005778Peroxisomal membraneIDAcellular_component
GO:0006066Alcohol metabolic processIDAbiological_process
GO:0008202Steroid metabolic processIDAbiological_process
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0016655Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorIDAmolecular_function
GO:0018455Alcohol dehydrogenase [NAD(P)+] activityIDAmolecular_function
GO:0042180Cellular ketone metabolic processIDAbiological_process
GO:0051262Protein tetramerizationIDAbiological_process
GO:0055114Oxidation-reduction processIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08764168530.99755304890.62161595261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2363856073

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin ADB00162 NUTR00007 | APRD00486

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-181d-5pMIMAT0002821MIRT041172CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.