HCSGD entry for PPP1R13L
1. General information
| Official gene symbol | PPP1R13L |
|---|---|
| Entrez ID | 10848 |
| Gene full name | protein phosphatase 1, regulatory subunit 13 like |
| Other gene symbols | IASPP NKIP1 RAI RAI4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003215 | Cardiac right ventricle morphogenesis | IEA | biological_process |
| GO:0003229 | Ventricular cardiac muscle tissue development | IEA | biological_process |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008134 | Transcription factor binding | TAS | molecular_function |
| GO:0009791 | Post-embryonic development | IEA | biological_process |
| GO:0031076 | Embryonic camera-type eye development | IEA | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0042633 | Hair cycle | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0048871 | Multicellular organismal homeostasis | IEA | biological_process |
| GO:0060048 | Cardiac muscle contraction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6304870332 | 0.0153479199 | 0.9999902473 | 0.2432496087 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -2.4925404696 |
| GSE13712_SHEAR | Down | -0.1711058402 |
| GSE13712_STATIC | Up | 0.2698393736 |
| GSE19018 | Up | 0.1647031025 |
| GSE19899_A1 | Down | -0.0421230625 |
| GSE19899_A2 | Down | -0.7468673232 |
| PubMed_21979375_A1 | Down | -0.1969597379 |
| PubMed_21979375_A2 | Down | -0.4069336168 |
| GSE35957 | Up | 0.0235301858 |
| GSE36640 | Down | -1.0084399142 |
| GSE54402 | Down | -0.2683844759 |
| GSE9593 | Down | -0.6125817128 |
| GSE43922 | Up | 0.0536921885 |
| GSE24585 | Up | 0.0858001139 |
| GSE37065 | Up | 0.0129315821 |
| GSE28863_A1 | Down | -0.2103781239 |
| GSE28863_A2 | Down | -0.0474658114 |
| GSE28863_A3 | Up | 0.3343980249 |
| GSE28863_A4 | Down | -0.0201868487 |
| GSE48662 | Up | 0.3676016901 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT004042 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004042 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
