HCSGD entry for SRCAP
1. General information
| Official gene symbol | SRCAP |
|---|---|
| Entrez ID | 10847 |
| Gene full name | Snf2-related CREBBP activator protein |
| Other gene symbols | DOMO1 EAF1 FLHS SWR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0004402 | Histone acetyltransferase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016573 | Histone acetylation | TAS | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5264024011 | 0.7113786558 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0015286748 |
| GSE13712_SHEAR | Up | 0.1788658970 |
| GSE13712_STATIC | Up | 0.0178952863 |
| GSE19018 | Down | -0.0062346105 |
| GSE19899_A1 | Up | 0.0140952393 |
| GSE19899_A2 | Up | 0.0009225155 |
| PubMed_21979375_A1 | Down | -0.2037016967 |
| PubMed_21979375_A2 | Down | -0.0119069367 |
| GSE35957 | Down | -0.1168644383 |
| GSE36640 | Down | -0.3035133486 |
| GSE54402 | Up | 0.0730276728 |
| GSE9593 | Up | 0.0237568676 |
| GSE43922 | Up | 0.1757777508 |
| GSE24585 | Down | -0.4509130527 |
| GSE37065 | Down | -0.0154817656 |
| GSE28863_A1 | Up | 0.1805601933 |
| GSE28863_A2 | Up | 0.0807364835 |
| GSE28863_A3 | Up | 0.1098743106 |
| GSE28863_A4 | Up | 0.2856639107 |
| GSE48662 | Up | 0.1997694288 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036303 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036817 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037418 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038290 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038471 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040165 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041967 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044623 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-194-5p | MIMAT0000460 | MIRT044873 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046182 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048104 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050747 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051752 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051910 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
