HCSGD entry for WASF3
1. General information
| Official gene symbol | WASF3 |
|---|---|
| Entrez ID | 10810 |
| Gene full name | WAS protein family, member 3 |
| Other gene symbols | Brush-1 SCAR3 WAVE3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0007010 | Cytoskeleton organization | IMP | biological_process |
| GO:0008360 | Regulation of cell shape | IMP | biological_process |
| GO:0014003 | Oligodendrocyte development | IEA | biological_process |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0030032 | Lamellipodium assembly | IEA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IEA | biological_process |
| GO:0030041 | Actin filament polymerization | TAS | biological_process |
| GO:0031643 | Positive regulation of myelination | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4890864557 | 0.0904681775 | 0.9999902473 | 0.5715837734 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3745572435 |
| GSE13712_SHEAR | Down | -0.9564449736 |
| GSE13712_STATIC | Down | -0.7819112277 |
| GSE19018 | Down | -0.2549101627 |
| GSE19899_A1 | Down | -0.8435366017 |
| GSE19899_A2 | Up | 0.1761456285 |
| PubMed_21979375_A1 | Down | -0.7388611863 |
| PubMed_21979375_A2 | Up | 0.0208544699 |
| GSE35957 | Up | 0.2827578668 |
| GSE36640 | Up | 0.3321938505 |
| GSE54402 | Up | 0.3948883498 |
| GSE9593 | Up | 0.3402753025 |
| GSE43922 | Up | 0.0044986652 |
| GSE24585 | Down | -0.2716122026 |
| GSE37065 | Up | 0.1526691724 |
| GSE28863_A1 | Up | 0.0887086935 |
| GSE28863_A2 | Up | 0.0415595551 |
| GSE28863_A3 | Up | 0.0284230909 |
| GSE28863_A4 | Up | 0.0490643823 |
| GSE48662 | Down | -0.3506637610 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-200b-3p | MIMAT0000318 | MIRT004296 | Luciferase reporter assay//qRT-PCR | Functional MTI | 19801681 |
| hsa-miR-429 | MIMAT0001536 | MIRT004437 | Luciferase reporter assay | Functional MTI | 19801681 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT004524 | Luciferase reporter assay | Functional MTI | 19801681 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 19801681 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
