HCSGD entry for HSPH1
1. General information
| Official gene symbol | HSPH1 |
|---|---|
| Entrez ID | 10808 |
| Gene full name | heat shock 105kDa/110kDa protein 1 |
| Other gene symbols | HSP105 HSP105A HSP105B NY-CO-25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006950 | Response to stress | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | TAS | biological_process |
| GO:0043014 | Alpha-tubulin binding | IEA | molecular_function |
| GO:0045345 | Positive regulation of MHC class I biosynthetic process | TAS | biological_process |
| GO:0051085 | Chaperone mediated protein folding requiring cofactor | IEA | biological_process |
| GO:0051135 | Positive regulation of NK T cell activation | TAS | biological_process |
| GO:0071682 | Endocytic vesicle lumen | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2313353102 | 0.0933726302 | 0.9149762134 | 0.5819895148 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8664064765 |
| GSE13712_SHEAR | Down | -0.0646818778 |
| GSE13712_STATIC | Up | 0.1636754022 |
| GSE19018 | Down | -1.6021378548 |
| GSE19899_A1 | Up | 0.0092680938 |
| GSE19899_A2 | Down | -0.3501042793 |
| PubMed_21979375_A1 | Down | -0.3516614182 |
| PubMed_21979375_A2 | Down | -0.4402093294 |
| GSE35957 | Down | -0.0839048326 |
| GSE36640 | Down | -0.0968521627 |
| GSE54402 | Up | 0.5695765998 |
| GSE9593 | Down | -0.0349175611 |
| GSE43922 | Down | -0.0156413404 |
| GSE24585 | Down | -0.4040661272 |
| GSE37065 | Up | 0.3052035998 |
| GSE28863_A1 | Up | 0.0871711670 |
| GSE28863_A2 | Up | 0.4674069316 |
| GSE28863_A3 | Down | -0.3348510082 |
| GSE28863_A4 | Up | 0.2203653371 |
| GSE48662 | Down | -0.2078428636 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031808 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041390 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT048010 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049463 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
