HCSGD entry for RPP40
1. General information
| Official gene symbol | RPP40 |
|---|---|
| Entrez ID | 10799 |
| Gene full name | ribonuclease P/MRP 40kDa subunit |
| Other gene symbols | RNASEP1 bA428J1.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004526 | Ribonuclease P activity | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005655 | Nucleolar ribonuclease P complex | TAS | cellular_component |
| GO:0008033 | TRNA processing | IEA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0674976901 | 0.0942633829 | 0.5593321485 | 0.5848907355 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4654093633 |
| GSE13712_SHEAR | Up | 0.6039818714 |
| GSE13712_STATIC | Up | 0.2331112646 |
| GSE19018 | Down | -0.8650017685 |
| GSE19899_A1 | Up | 0.0423550952 |
| GSE19899_A2 | Up | 0.8115418149 |
| PubMed_21979375_A1 | Up | 1.3462206430 |
| PubMed_21979375_A2 | Up | 0.7278694205 |
| GSE35957 | Down | -1.0646597558 |
| GSE36640 | Up | 0.3605954960 |
| GSE54402 | Up | 0.2876452123 |
| GSE9593 | Down | -0.3173555340 |
| GSE43922 | Up | 0.2814012370 |
| GSE24585 | Down | -0.5935036742 |
| GSE37065 | Down | -0.0340819135 |
| GSE28863_A1 | Down | -0.2879280433 |
| GSE28863_A2 | Up | 0.0539332744 |
| GSE28863_A3 | Down | -0.5249329819 |
| GSE28863_A4 | Up | 0.0191895091 |
| GSE48662 | Down | -0.8429289661 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023880 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028558 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
